San José de Chiquitos
By trainYou can come by Red Oriental (http://www.ferroviariaoriental.com/) train (aka "death train") both from Santa Cruz and Puerto Quijarro.
By busUp to two buses daily come from San Ignacio passing San Miguel and San Rafael on the way (all dirt road), Bs50. There are bus connections from Santa Cruz (paved road) as well.
By footSan José is small enough to walk on foot.
By motoMototaxis are available.
The church complex (church, belltower, museum)In contrast to other missions with a lot of wood constructions, the church complex of San José is made from adobe bricks, stones and plaster. The complex is nicely restored.
Visit Santa Cruz la Vieja historical national parkBeing a mix of nature and history this is where the city of Santa Cruz was first founded. The foundation site is marked with some crosses on a hill and still has some remains of ancient urban planning (i.e. streets). You can continue up the hill for the viewpoint (mirador) over San José and rock formation place. The walk can be tiring on a sunny day, because of much exposure to the sun - take enough water with you. It may be a good idea to call a mototaxi (i.e. Adam Mototaxi, tel. 73981271, or Alex Mototaxi, tel. 77388714) in San José to come and take you back into town (Bs20). The nature in the park is at its most beautiful during the wet season.
Climb Cerro TurubóA magnificent hill that stands out of the plain landscape and offers excellent views (if no mist or smog). The hike is tiring on the paved road, but delighting on the pathway (partly goes through the forest).
Sabor y ArteKind of expensive (salad + 1,5 l lime drink is Bs50), bus nice service and interior.
A guesthouse at Chiquitano-Ayoreo museumphone: +591 73988222 (ask for Mary)address: Calle Ovidio BarbeayCalm place with good personnel.
For more Chiquitania and Pantanal experiences you want to go (by quite frequent buses or not-so-frequent trains) east to Roboré (and definitely visit nearby Santiago de Chiquitos) or Puerto Quijarro (to see and cross the river Paraguai for visiting nice town Corumbá in Brasil). Try to arrange a stop at the little town of Chochís as it is a mind-boggling place.
You can as well go west to Santa Cruz by quite frequent buses or Red Oriental train.